Antimicrobial Properties and Preliminary Phytochemical Screening of Chromolaena odorata (Siam or Sapysa Weed) Leaf
Abstract
Ethanolic extract of fresh leaves of Chromolaena odorata was screened for its phytochemical and in-vitroantibacterial properties on the following hospital isolates: Escherichia coli, Proteus mirabilis, Pseudomonasaeruginosa, Klebsiella pneumoniae and Staphylococcus aureus. The disc diffusion technique was used to assay forthe antimicrobial properties and the results showed that the extracts at different concentrations inhibited the growthof all test organisms. The minimum inhibitory concentrations (MIC) determined by the tube dilution method were31.25mg/ml for Staphylococcus aureus and Pseudomonas aeruginosa, 62.5mg/ml for E.coli and Klebsiellapneumonia, respectively. The phytochemical screening of the leaf extract revealed the presence of tannins,phylobatannins, saponins, flavonoids, alkaloids and glycosides, some of which may have contributed to the observedantibacterial activity.
Author(s)
Inyang C. U. , Adegoke A. A., Nlemorisa Remi
Full Text | Article Number: NJM_14_22_7
